Product: Mannitol
Standard: CP2005, BP2000, BP2005, USP28, USP29,
Packing: 25KG/ kraft paper Bag, 14MT/20FCL; 25KG/Fibre drum, 9MT/20FCL
CAS No.: 87-78-5
Molecular formula: C6H14O6
Molecular Weight: 182.178

Mannitol is colorless crystalline powder, odor free and with sweet taste, it is easily dissolve in water and slightly dissolve in ethyl alcohol.
Injection material: Used in producing the mannitol injection solution, reducing the encephalic pressure, the intraocular pressure etc.

Excipient of filler for tablets:
Used in the anticancer drug, antibacterial, antihistamine medicine, in vitamin, drunk awaking drug, the mouth freshener tablet and so on. Vasodilator medicine for blood vessel for brain: Used in treating the blood vessel blocked of brain.
Diuretic stuff:
Mannitol is a kind of mild laxative lapactic, which has a special curative effect to oliguria and the kidney function failure caused by dropsy, burnt and so on.


Item CP2000 BP 2000 USP24
Appearance White crystalline powder; odorless, sweet taste White crystalline powder, soluble in water, slightly soluble in ethanol, non-soluble in aether White crystalline powder, soluble in water, slightly soluble in ethanol, non-soluble in aether
Melting point 166 ~ 170 165 ~ 170 164 ~ 169
Identification Pass on test Pass on test Pass on test
Acidity or Basicity ≤0.3ml of 0.02mol/L NaOH ≤0.3ml of 0.01mol/L HCL or≤0.2ml of 0.01mol/L NaOH ≤0.3ml of 0.02mol/L NaOH
Clarity and color of Solution Clear and colorless Clear and colorless  
Chloride % ≤0.003 ≤0.005 ≤0.007
Sulphate % ≤0.010 ≤0.010 ≤0.01
Oxalate % ≤0.020    
Residue on ignition % ≤0.1 ≤0.1  
Loss on drying % ≤0.5 ≤0.5 ≤0.3
Arsenic % ≤0.0002   ≤0.0001
Heavy metals % ≤0.001 ≤0. 00005  
Nickle %   ≤0.0001  
Specific optical rotation   +23°+25°(in borax solution) +137°+145° (in ammonium molybdate solution)
Reducing sugars     No more than few deposit
Assay % 98.0 ~ 102.0 98.0 ~ 101.5 96.0 ~ 101.5
Sorbitol %   ≤2  
Bacterial endotoxin   <100g/l of mannitol,≤4 I.U./g≥100g/l of mannitol,≤2.5 I.U./g  

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